Spider Hero Fighting

The boss fights, destructive combat, use of an original story about Spider Hero.

The game received generally positive reviews from critics, who singled out the boss fights, destructive combat, use of an original story, voice acting and open-ended nature. However, the game's choice system received mixed reviews; although some praised how the player is able to create a dynamic experience with their choices, others were critical of the system's limitations. In addition, reviewers criticized the storyline' s poor execution, bothersome camera controls, the inability to free-roam after completing the game, lip-synching issues and the ugly graphics.

There are multiple endings depending on how the game is played out. In addition, the player can choose which villains to fight against. The player is able to switch between Spider Hero traditional red and blue costume and the symbiote suit at any time during gameplay.

Spider Hero runs into Wolverine after a battle, the two settle their differences and begin tracking down other infected citizens. Eventually, Spider Hero finds Venom throwing people into symbiote pods, turning them into monsters. The two engage in a cross-city battle in which Venom escapes and several of the pods are destroyed. A S.H.I.E.L.D. team led by Black Widow arrives quarantines New York and sets up symbiote controlled citizen quarantine camps. Electro rampages through the camps, looking for his sister; Widow shoots him to restore order. Electro's sister accidentally infects and heals him with the symbiote attached to her. The result is a powerful symbiote monster, who takes off before anything can be done to contain him.

Spider Hero decides to break the Tinkerer out of Ryker's to utilize his scientific genius to find a countermeasure to the symbiotes. Before leaving, the player must choose who should take him to prison (Moon Knight or Vulture). Upon reaching the prison, Spider Hero teams up with the Rhino, using his strength to help free the Tinkerer. At this point, Spider Hero may trick Rhino into getting incapacitated or break his moral code and allow Rhino to escape. With Wilson Fisk's support, the Tinkerer then designs a device that won't harm the hosts, only remove the symbiotes; it must be installed on the Trask Building for the maximum efficient sound waves. While the Tinkerer constructs the device, Spider Hero aids S.H.I.E.L.D. in dealing with the symbiote infestation in the streets of Manhattan and does some errands for Fisk. First, he confronts the symbiote Electro in Central Park, defeating him and stopping him from reaching the city's power supply. After defeating Electro, the player can choose to reach out to Electro so that he can remove the symbiote, or Spider Hero can remove it by force.